IRB Barcelona

Created in 2005 by the Generalitat de Catalunya (Government of Catalonia) and University of Barcelona, IRB Barcelona is a Severo Ochoa Centre of Excellence, a seal that was awarded in 2011. The institute is devoted to conducting research of excellence in biomedicine and to transferring results to clinical practice, thus improving people’s quality of life, while simultaneously promoting the training of outstanding researchers, technology transfer, and public communication of science. Its 27 laboratories and eight core facilities address basic questions in biology and are orientated to diseases such as cancer, metastasis, Alzheimer’s, diabetes, and rare conditions. IRB Barcelona is an international centre that hosts 400 employees and more than 30 nationalities. It is located in the Barcelona Science Park. IRB Barcelona is a CERCA center, and a member of the Barcelona Institute of Science and Technology (BIST).

Dr. Tiago Botelho
_{Senior business development manager}
tiago.botelho@irbbarcelona.org tiago.botelho@irbbarcelona.org
+34934020962 +34934020962
Carrer de Baldiri Reixac, 10, 08028 Barcelona, España

Ownership: Public
Research Group / Unit / Center / Plataform / Department: Drug Screening Platform

Organization type

Academic research institution
Foundation

Early phases

Biomarker identification
Omics
- Epigenomics
- Genomics
- Metabolomics
- Phenomics
- Proteomics
- Transcriptomics
Systems biology
Target identification – new biological hypothesis
Target validation – Hypothesis verification

Screening

Assay development
- In vitro screening models
Chemical libraries
- Small molecules (including natural product, DNA encoded libraries and fragment libraries)
Fragment based screening
- Virtual screening
Screening and high throughput screening using small molecules (including natural product, DNA encoded libraries and fragment libraries)

Optimization phases

In vitro biochemical models(including assay/model development and testing)
In vitro cellular and organotypic 3D models (including assay/model development and testing)

Functional areas

Artificial intelligence
Bioinformatics
Molecular and cellular biology
- Cell line generation
- Flow cytometry
- Gene editing
- Imaging / High content screening
- Mechanistic enzymology & receptorology
- Microarrays
- Protein expression / purification
- qPCR
- RNAseq
- Sequencing
Structural biology

Terapeutic areas

Autoimmunity / Inflammation
Blood and lymphatic system
Cancer
Infectious diseases
Metabolism / Endocrinology
Nervous Central System
Rare diseases

Additional activities

Consulting services
CROs providing no-regulatory and regulatory services for drug discovery
Government initiatives supporting drug and research collaborations
Industry associations
Investment / fund raising activities for drug discovery

Additional info

About the screening capabilities at IRB Barcelona

At the Drug Screening Platform (DSP), we provide expert support for Chemical Biology and Drug Discovery projects. Our platform accepts projects from the entire IRB Barcelona research community, as well as from external projects, both from academia and industry. Our expert team provides tailored experimental support for a wide range of targets and technologies during the Candidate Discovery phase, from High-Throughput Screening (HTS) to Lead Optimisation. The use of state-of-the-art equipment together with robust analysis software, allows you to run your projects following industrial standards in an accurate, fast and reliable manner.

We offer full drug discovery support tailored to researchers’ needs, from experimental design to wet-lab validation, with the possibility of chemo- and bioinformatics analysis. We assess theoretical feasibility in terms of the relevance of the assays, throughput level and technical feasibility. This is followed by assay development, accomplishing industrial standards. The instrumentation available in the DSP is compatible with libraries of small molecules, biological extracts, peptides, antibodies and other molecules.

More information here.

IRB Barcelona

Dr. Tiago Botelho

Organization type

Early phases

Screening

Optimization phases

Functional areas

Terapeutic areas

Additional activities

Additional info

About the screening capabilities at IRB Barcelona

Socios de ES-OPENSCREEN: