Instituto Investigación Sanitaria La Fe, Valencia

Additional info

The Drug Development and Innovation Support Unit works on the development and evaluation of new therapeutic agents directed at specific molecular targets using an approach based on rational drug design and metabolomics. To achieve these objectives, the DDU is working on the development of experimental strategies that allow the identification and characterization of pharmacological targets, as well as the search for new therapeutic principles against them.

These objectives are complemented with the identification of pharmacological / clinical biomarkers that can be used for the diagnosis / prognosis of different pathologies, the stratification and monitoring of patients, the characterization of the mechanism of action of drugs, and the evaluation of their safety profiles.

The Drug Development and Innovation Support Unit offers services focused on innovation and development of new diagnostic methods and therapies directed at specific molecular targets, using an approach based on rational drug design and metabolomics. In this context, the main services offered by the DDU are related to:

• Expression and purification of recombinant proteins
• Study of molecular interactions: NMR, SPR, ITC
• Fragment screening by NMR
• Preparation, measurement and analysis of metabolomics samples by NMR
• Integrated analysis of omics data
• Use of equipment by users external to the platform

These services are applicable in different areas, including mainly the development of new drugs and the development of new methods for the diagnosis and monitoring of patients.